MRSA and C. diff deaths falling
Deaths from MRSA fell by a quarter, from 485 in 2010 to 364 in 2011.
There were 2,053 C. difficile infections last year, compared with 2,704 the year before.
Earlier this year, the Health Protection Agency warned other infections were taking their place.
Both infections have shown large declines over the past five years after being repeatedly targeted by government policies.
However, there is some concern other infections such as E.coli appear to be rising.
The health minister, Simon Burns, said: "The news that MRSA deaths are lower than at any point in the last 15 years is a testament to the hard work and dedication of NHS staff across the country."
