Friday 29 April 2011

Screen may spot autism

Screen may spot autism in one-year-olds

baby check The screen could be added to the list of health checks normally carried out a the one-year screen
Asking parents a few simple questions about their baby during routine one-year well-baby checks can help spot early autism, say US experts.
The condition, which affects how the child relates to other people, is usually only spotted some years later.
But enquiring about a child's use of eye contact, sounds, words and gestures can flag up early on if more detailed screening is needed, a study shows.
The findings in over 10,000 infants are published in the Journal of Pediatrics.
Of the 10,479 one-year-olds seen, 184 failed the initial check-up and were referred for further evaluation by the team at the University of California, San Diego School of Medicine.
To date, 32 have received a provisional or final diagnosis of autism spectrum disorder and another 101 have been found to have other conditions that involve developmental delay.
These rates, say the authors, are typical of what you might expect to see in a population of this size, suggesting that the screening could work.
Lead researcher Karen Pierce said: "Given lack of universal screening of infants for such disorders at 12 months, this programme could be adopted by any paediatric office, at virtually no cost, to aid in the identification of children with developmental delays.
"Importantly, parents will be able to get help for their children at a much earlier age than before."
Autism is a spectrum condition, which means that, while all people with autism share certain difficulties, their condition will affect them in different ways.
Early diagnosis
Some people with autism are able to live relatively independent lives but others may have accompanying learning disabilities and need a lifetime of specialist support.
The sooner the condition is diagnosed, the quicker they can access the care available.
Carol Povey, Director of the National Autistic Society's Centre for autism, said: "We welcome research which could help autism be diagnosed earlier.
"Whilst a formal diagnosis requires a comprehensive clinical assessment, screening checks at key developmental stages can help professionals identify children who may be showing signs of autism."



    Friday 8 April 2011

    Monkeys 'harbour malaria threat'

    Monkeys 'harbour malaria threat'

    Monkeys A type of malaria could move from monkeys to humans, say scientists

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    Scientists are warning that a species of malaria could switch from targeting monkeys to humans.

    Macaques in south east Asia are a vast source of Plasmodium knowlesi which can spread to people, they write in PLoS Pathogens.

    They believe that growing human populations and increased deforestation in the region could lead to the parasite switching host.

    But those changes could also reduce the spread of the disease.

    Around one million people die each year as a result of malaria.

    It is caused by parasites and is spread by mosquitoes when they drink blood.

    'Huge reservoir'

    P. knowlesi is known as the fifth malarial parasite in humans.

    It mostly exists in monkeys, however, there have been human cases and it has been shown in the laboratory to be able to spread from human to human.

    Start Quote

    With increasing human populations and deforestion we may get a shift to humans”

    End Quote Professor Balbir Singh University Malaysia Sarawak

    In south east Asia, the macaques are the second most common primate after humans.

    Blood tests on 108 wild macaques showed that more than three quarters were infected with the malaria parasite.

    Professor Balbir Singh, from the Malaria Research Centre at Universiti Malaysia Sarawak, told the BBC: "they are a huge reservoir of Plasmodium knowlesi."

    Genetic analysis showed that P. knowlesi had existed in monkeys since before humans settled in south east Asia. The researchers said humans were being infected from the 'reservoir', rather than the disease spreading between humans.

    Prof Singh raised concerns about what could happen in the future: "We don't know how mosquito behaviour will change.

    "With increasing human populations and deforestation we may get a shift to humans. The number of malaria cases is coming down so there is also decreased immunity. Or would deforestation reduce numbers? It could go either way."

    Dr Hilary Ranson, from the Liverpool School of Tropical Medicine, said: "It seems a very reasonable thing to speculate.

    "Deforestation or any perturbation of the ecosystem frequently leads to humans being exposed to an expanded range of biting insects and the pathogens they transmit, yellow fever is a good example of this."

    She said if humans catch the parastite more often then P knowlesi may evolve to target humans.

    "To me the important message is that disruption of the environment exposes people to a range of known and potentially unknown pathogens transmitted by blood feeding insects that do not typically feed on humans" she added.

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