Thursday, 20 April 2017

alchemists

34 CHRONICLES OF PHARMACY xvi
Pearls, writes Jean de Renou (1607), “are greatly cordial and rejoice the heart. The alchemists consequently make a liquor of pearls, which they pretend is a marvellous cure for many maladies. More often than not, however, their pretended liquor is nothing hut smoke, vanity, and quackery. I knew a barber in this city of Paris who was sent for by a patient to apply two leeches, and who had the impudence to demand six crowns of gold for his service. He declared that he had fed those leeches for an entire month on the liquor of pearls.”
,It is on record that Pope Clement VII took 40,000 ducats’ worth of pearls and other precious stones with unicorn’s horn within fourteen days. (See Mrs. Henry Cust’s “ Gentlemen Errant.”)
Emeralds had a great reputation, especially on account of their moral attributes. They were cold in an extra first degree, so cold that they became emblems of chastity, and curious tales of their powers in controlling the passions were told. Moses Maimonides, a famous Jew who lived in Egypt in the twelfth century, in a treatise he wrote by command of the Caliph as a concise guide in cases of venomous bites or poisons generally, declared that emeralds were the supreme cure. They might be laid on the stomach or held in the mouth or 9 grains of the powdered stone might be taken in wine. But recognising that emeralds were not always handy when the need arose, Moses names a number of more ordinary remedies.
Confection of Hyacinth was a noted compound formulated in all the old pharmacopoeias, and regarded as a sovereign cordial, fortifying the heart, the stomach, and 'the brain ; resisting the corruption of the humours and the malignity of the air ; and serving for many oi lier medicinal purposes. The original formula ordered Ih•sides hyacinths (which were probably amethysts), sapphires, emeralds, topazes, and pearls; silk; gold and silver leaves; musk, ambergris, myrrh, and camphor; sealed earth, coral, and a few vegetable drugs ; all made into an electuary with syrup of carnations. A similar compound, but in powder ^form, was known as “ Hungary Powder” and was believed to have been the most esteemed remedy in the Hungary Fever, to which some reference is made in the sketch of Glauber (Vol. I, pp. 260-264). The Emperor Ferdinand’s Plague I’owder was another variation of the same compound. Tliii formula given in Fernery’s Pharmacopoeia orders about twenty vegetable drugs with bole, hartshorn, ivory, and one scruple each of sapphires, hyacinths, emeralds, rubies, and garnets, in a total bulk of about I minces. The dose was from ^ scruple to 2 scruples.
Sir William Bulleyn, a famous physician in the reign of Henry VIII, and said to have been of the same family as the Queen, Anne Boleyn, in his “ Book of Simples,” which was a work of great renown in its day, gives the following recipe for Electuarium de Gemmis. " Take 2 drachms of white perles; two little peeces of nphyre; jacinthe, corneline, emerauldes, granettes, of eiieh an ounce; setwal, the sweate roote doronike, I lie rind of pomecitron, mace, basel seede, of each drachms; redde corall, amber, shaving of ivory, of each 2 drachms; rootes both of white and red behen, ginger, long pepper, spicknard, folium indicum, saffron nmlamon, of each one drachm ; troch diarodon, lignum aloes, of each half a small handful; cinnamon, galinga, /,nruboth, which is a kind of setwal, of each 1|- drachm :
I Inn pieces of gold and sylver, of each half a scruple; iiiii k, half a drachm.” The electuary was to be made

Friday, 24 March 2017

Landowners' trees blamed for knocking down Tarr Steps


Rebuilding Tarr StepsImage copyrightSOMERSET COUNTY COUNCIL
Image captionThe stones, some weighing up to two tonnes, were put back into place on Thursday

Calls have been made for landowners to manage their woodlands better to help prevent the stones of an ancient bridge in Exmoor being washed away.
The Tarr Steps in Exmoor National Park across the River Barle were knocked out of place during storms in November.
Conservation manager Rob Wilson North said the "big problem" was "the water bringing fallen debris from the woodland".
The bridge has now been rebuilt for the second time in four years.

'Jewel in the crown'

Mr Wilson North, who works for the national park, added landowners must share some of the blame and manage their land better.
Tarr Steps is made up of 17 spans and stretches nearly 164ft (50m) across the river.
Its exact age is unknown, with several theories claiming Tarr Steps date from the Bronze Age, while others date them to about 1400 AD.
The repair work involved putting the pieces together - with some weighing up to two tonnes - much like a jigsaw as each stone is numbered.
Cabinet member for highways at Somerset County Council, David Fothergill, said: "It is an ancient scheduled monument, it's Grade I listed.
"It attracts huge numbers of people to Exmoor in terms of tourism and the local economy, it's the jewel in the crown for Exmoor and we do need to look after it."

Rebuilding Tarr StepsImage copyrightSOMERSET COUNTY COUNCIL
Image captionSomerset County Council is responsible for the upkeep of the ancient bridge

Tarr Steps has been damaged many times throughout its long history, most recently in 2013.
Due to its protected status, the bridge must be put together exactly as before.
The council added that additional work had taken place to repair an upstream "tree protection boom" to prevent trees falling into the river and hitting the bridge.
It also said the Tarr Steps could be better protected if landowners did not stack timber along the river.

Rebuilding Tarr StepsImage copyrightSOMERSET COUNTY COUNCIL
Image captionThe bridge has been washed away twice in four years

Related Topics

The vanity of cruelty

Drug 'reverses' ageing in animal tests


Old personImage copyrightGETTY IMAGES

A drug that can reverse aspects of ageing has been successfully trialled in animals, say scientists.
They have rejuvenated old mice to restore their stamina, coat of fur and even some organ function.
The team at Erasmus University Medical Center, in the Netherlands, are planning human trials for what they hope is a treatment for old age.
A UK scientist said the findings were "impossible to dismiss", but that unanswered questions remained.
The approach works by flushing out retired or "senescent" cells in the body that have stopped dividing.
They accumulate naturally with age and have a role in wound healing and stopping tumours.
But while they appear to just sit there, senescent cells release chemicals that cause inflammation and have been implicated in ageing.
The group of scientists created a drug that selectively killed senescent cells by disrupting the chemical balance within them.
"I got very rebellious, people insisted I was crazy for trying and for the first three times they were right," Dr Peter de Keizer told the BBC.

'Crazy'

On the fourth attempt he had something that seemed to work.
He tested it on mice that were just old (the equivalent of 90 in mouse years), those genetically programmed to age very rapidly and those aged by chemotherapy.
The findings, published in the journal Cell, showed liver function was easily restored and the animals doubled the distance they would run in a wheel.
Dr de Keizer said: "We weren't planning to look at their hair, but it was too obvious to miss."

MiceImage copyrightPETER DE KEIZER

He also said there were a lot of "grey" results - things that seemed to improve in some mice but not all.
The drug was given three times a week and the experiments have been taking place for nearly a year.
There are no signs of side-effects but "mice don't talk", Dr de Keizer said. However, it is thought the drug would have little to no effect on normal tissues.
When asked if this was a drug for ageing, Dr Keizer told the BBC News website: "I hope so, but the proof of the pudding is in the eating as you say.
"In terms of mouse work we are pretty much done, we could look at specific age-related diseases eg osteoporosis, but we should now prepare for clinical translation."
Commenting on the results, Dr Dusko Ilic, a stem cell scientist at King's College London, said: "The finding is impossible to dismiss.
"[But] until more high-quality research is done, it is better to be reserved about these findings.
"Though, I would not be surprised if manufacturers try to capitalise on this and, in a few years, we could buy this peptide as a supplement over the counter."
Prof Ilaria Bellantuono, Professor in Musculoskeletal Ageing, University of Sheffield, called for further tests on "heart, muscle, metabolic, cognitive function" to take place.
But added: "The use of this peptide in patients is a long way away.
"It requires careful consideration about safety, about the appropriate group of patients for whom this peptide can be beneficial in a reasonable period of time so that positive effects can be easily measured at an affordable cost."

Monday, 20 March 2017

NHS services in England are facing a "mission impossible"

NHS facing 'mission impossible next year'

  • 19 March 2017
  •  
  • From the sectionHealth


A hospital wardImage copyrightPA

NHS services in England are facing a "mission impossible" to meet the standards required by the government, health bosses say.
The warning has been made by NHS Providers, which represents hospital, mental health and ambulance trusts.
It said front-line services simply do not have enough money - and predicts longer waits for hospital operations and more delays in A&E as a result.
But ministers said the NHS has been given the money it needs.
The NHS budget is increasing this Parliament, but not by as much as the health service has traditionally got.
NHS Providers predicts its members, which account for nearly two-thirds of health spending, will get £89.1bn in 2017-18 - that is 2.6% more than they got this year, but crucially just half of the 5.2% demand is expected to grow by.

Patient safety 'at risk'

Chief executive Chris Hopson said it was time for the government to "sit up and listen".
He described the goals for next year - to get back to hitting the waiting time targets for A&E and hospital operations, while balancing the budget - as "mission impossible".
"NHS trusts will strain every sinew to deliver the commitments made for the health service. But we now have a body of evidence showing that, with resources available, the NHS can no longer deliver what the NHS constitution requires of it.
"We fear that patient safety is increasingly at risk."
The analysis carried out by NHS Providers predicts that the numbers waiting in A&E longer than the four-hour target will increase by 40% next year to 1.8m, while the numbers waiting beyond the 18-week target for routine treatments, such as knee and hip operations, will go up by 150% to around 100,000.
A Department of Health spokeswoman said extra money was being invested in the NHS and pointed out the Budget had set aside more funding for social care, which would also help relieve the pressures on hospitals in particular.
She added the government had a "strong plan to improve performance" and accused NHS Providers of failing to acknowledge the steps that were being taken.


graph

Related Topics

Care firms have cancelled contracts with 95 UK councils, saying they cannot deliver services for the amount they are being paid

'Lack of money' prompts care firms to end council contracts

  • 47 minutes ago
  •  
  • From the sectionUK


Carer with womanImage copyrightGETTY IMAGES

Care firms have cancelled contracts with 95 UK councils, saying they cannot deliver services for the amount they are being paid, a BBC Panorama investigation has found.
Some firms said they could not recruit or retain the staff they needed.
The Local Government Association said it was the result of "historic under-funding" and an ageing population.
The government declined an interview but said English councils had received £9.25bn for social care.
The figure for the number of cancelled contracts comes from a Freedom of Information request, which was responded to by 197 of 212 UK councils.
According to the research, carried out for Panorama by Opus Restructuring and Company Watch, 69 home care companies have closed in the last three months and one in four of the UK's 2,500 home care companies is at risk of insolvency.
Councillor Izzi Seccombe from the Local Government Association - which represents councils across England and Wales - said: "We have warned that the combination of the historic under-funding of adult social care, and the significant pressures of an ageing population and the national living wage, are pushing the care provider market to the brink of collapse.
"These figures show the enormous strain providers are under, and emphasises the urgent need for a long-term, sustainable solution to the social care funding crisis."
Many home care companies say their biggest problem is recruitment and retention of carers.
The Centre for Workforce Intelligence estimates at least two million more carers will be needed by 2025 in England alone, in both in-home care and care homes, to cope with growing demand.
Last October, the regulator for England, the Care Quality Commission, warned that adult social care was at a tipping point.


Care worker Amanda Hopewell
Image captionThere are 800,000 home care workers in the UK

One home care company, Cymorth Llaw, which had contracts with three councils in north Wales, told Panorama it had recently stopped working with one - Conwy, which had initially paid £14.20 an hour for care.
It offered to raise that to £15, but the company decided that still wasn't enough and handed back the contract.
Ken Hogg, at Cymorth Llaw, said: "We didn't think we could do it for the money - it was as simple as that.
"We pay as much [in wages] as we possibly can and we've always paid above what was the national minimum wage and the national living wage.
"[Carers] get a mileage allowance, they get paid travelling time between their clients."


Ken Hogg
Image captionKen Hogg says council funding barely covers his care home company's costs

Mr Hogg said the company was legally obliged to pay 1% pension and 13.8% national insurance contributions, along with training and other staff-associated costs, which "doesn't leave a great deal".
Conwy Council said it was committed to supporting vulnerable people in communities, despite the financial challenges.
Home care company Mears used to have a contract with Liverpool City Council but cancelled it in July, saying £13.10 an hour was not enough to cover costs.
Mears said it needed at least £15 an hour, and like other companies across the UK, argued its costs are often greater than what councils pay.
Alan Long, executive director at Mears, said: "That was a terrible thing to do for both service users and for care staff.
"We absolutely did not take that lightly, but frankly what choice did we have?
"We just cannot do the two most basic things that you need to do in home care - pay staff the absolute minimum of a living wage and be able to recruit enough people to deliver the service that Liverpool Council actually expected from us."

Bed shortages

The industry's trade body, the United Kingdom Homecare Association, said many companies were really struggling.
Colin Angel, its policy and campaigns director, said some care providers are "really desperate" and "really do not know whether they're going to be able to continue in business, beyond the next year".
He added: "That means they're really having to make some hard commercial decisions, whether they might need to cease trading or indeed just hand back work to local councils."
The nationwide shortage of carers is leaving many elderly people stuck in NHS wards, which results in bed blocking.
Government figures show there are more than 6,500 people across Britain stuck in an acute hospital bed, despite being well enough to leave.
In England, a third of these are waiting for a home care package.


Colin Angel
Image captionColin Angel has concerns that more care home companies may close in the coming months

Mike Furlong, manager of the Granby Rehabilitation Unit in Liverpool, told Panorama that while on average people spend 28 days at the care facility, "some patients have been with us 12 and 14 weeks because all the therapy is complete, but unfortunately there's no care package available at the end of it".
Liverpool City Council said that, over the last seven years, its budget had been cut by £330m and it now needed to find a further £90m over the next three years.
Samih Kalakeche, Liverpool's director of adult social services, said: "Is there a crisis in the home care services? I'll say yes, there is - and it's not just money, it's the sheer volume of demographics.
"We've got an ageing population which we welcome, but we don't have enough people coming into the industry."

'£2bn extra'

Earlier this month, Chancellor Philip Hammond announced £2bn extra for social care for English councils over the next three years.
Scotland, Northern Ireland, and Wales will decide how they spend their extra funding.
But the industry says that with an increasingly ageing population, it's just not enough to keep pace with demand.
The government has said it will be bringing forward more proposals later this year, to ensure a financially sustainable social care system.
Panorama: Britain's Home Care Crisis - Monday, 20 March, 20:30 GMT, BBC One

Featured post

More patients in Scotland given antidepressants

More patients in Scotland given antidepressants 13 October 2015   From the section Scotland Image copyright Thinkstock Image ca...