Showing posts with label antibiotics. Show all posts
Showing posts with label antibiotics. Show all posts

Friday 25 January 2013

Antibiotic 'apocalypse' warning


Antibiotic 'apocalypse' warning

Tuberculosis bacteriaDrug resistance is a problem in tuberculosis

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The rise in drug resistant infections is comparable to the threat of global warming, according to the chief medical officer for England.
Prof Dame Sally Davies said bacteria were becoming resistant to current drugs and there were few antibiotics to replace them.
She told a committee of MPs that going for a routine operation could become deadly due to the threat of infection.
Experts said it was a global problem and needed much more attention.
Antibiotics have been one of the greatest success stories in medicine. However, bacteria are a rapidly adapting foe which find new ways to evade drugs.
MRSA rapidly became one of the most feared words in hospitals wards and there are growing reports of resistance in strains of E. coli, tuberculosis and gonorrhoea.
Prof Davies said: "It is clear that we might not ever see global warming, the apocalyptic scenario is that when I need a new hip in 20 years I'll die from a routine infection because we've run out of antibiotics."
She said there was only one useful antibiotic left to treat gonorrhoea.
"It is very serious, and it's very serious because we are not using our antibiotics effectively in countries.

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We have to be aware that we aren't going to have new wonder drugs coming along because there just aren't any.”
Prof Hugh PenningtonUniversity of Aberdeen
"There is a broken market model for making new antibiotics, so it's an empty pipeline, so as they become resistant, these bugs, which they would naturally but we're breeding them in because of the way antibiotics are used, there will not be new antibiotics to come."
Possible solutions will be included in her annual report to be published in March.
Empty arsenal
The World Health Organization has warned the world is heading for a "post-antibiotic era" unless action is taken.
It paints a future in which "many common infections will no longer have a cure and, once again, kill unabated".
Conservative MP Stephen Metcalfe warns that research is not happening quickly enough.
Prof Hugh Pennington, a microbiologist from the University of Aberdeen, said drug resistance was "a very, very serious problem".
"We do need to pay much more attention to it. We need resources for surveillance, resources to cope with the problem and to get public information across.
But he said it was not a problem entirely of the UK's making.
"People are going abroad for operations, going abroad for, let's say, sex tourism and bringing home gonorrhoea which is a big problem in terms of antibiotic resistance - and then there's tuberculosis in many parts of the world.
Prof Pennington said the drugs companies had run out of options too as all the easy drugs had been made.
"We have to be aware that we aren't going to have new wonder drugs coming along because there just aren't any."

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Sunday 27 November 2011

EU Parliament Votes To Oppose Most Farm Antibiotic Use

EU Parliament Votes To Oppose Most Farm Antibiotic Use     mengele-westof
A quick post, because I’m on a ferocious deadline, but still can’t let this news go by. In a vote that’s non-binding but high profile and influential, the European Parliament has resolved to end “prophylactic use” of antibiotics in farming, and to prevent any “last resort” antibiotics from being used in animals, in order to keep resistance from developing so that the drugs will still be effective in human medicine.
This is a significant development. The European Union has already banned “growth promotion,” the use of micro-doses of antibiotics that cause meat animals to fatten more quickly. What the Parliament is doing here is asking the European Commission, the EU’s law-making body, to add “disease prevention” use to the ban. That’s the delivery of treatment-strength doses of antibiotics to all animals on a farm in order to prevent their becoming ill as a result of the confinement conditions in which they are held. It accounts for a substantial portion of the antibiotics used in agriculture, and is a major driver of the emergence of antibiotic-resistant organisms.
The “Resolution on the Public Health Threat of Antimicrobial Resistance” says, in part, that the body:
29.  Calls on the Commission to make legislative proposals to phase out the prophylactic use of antibiotics in livestock farming;
30.  Stresses that the livestock and intensive fish-farming sectors should focus on preventing disease through good hygiene, housing and animal husbandry, as well as strict bio-security measures, rather than the prophylactic use of antibiotics;
31.  Calls, in particular, for the establishment of good practices for animal husbandry which minimise the risk of antimicrobial resistance; emphasises that these practices should in particular apply to young animals brought together from different breeders thus increasing the risk of communicable diseases;…
33.  Calls for a separation between the active ingredients and effect mechanisms used in human medicine and veterinary medicine, to the extent possible, to reduce the risk of resistance against antibiotics being transferred from livestock to humans, but points out that this must not result in the imposition of restrictions on existing treatment options that are effective;
34.  Considers that the use of so called ‘last resort’ antibiotics targeting problematic human pathogens should be permitted for agricultural use only under licensed conditions combined with resistance monitoring, preferably on an individual basis…
For a quick read, here’s the press release, and for a longer one, here’s the full resolution, which admirably tackles overuse and misuse of antibiotics in human medicine, shortfalls in drug development, and the need for new quick diagnostics as well. Note also that it does not forbid the use of antibiotics to treat individual sick animals; no one that I am aware of has ever argued against that. According to the UK paper Farmers’ Guardian, agricultural unions are already objecting.
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Wednesday 9 November 2011

Antibiotic resistance is driven by overusing antibiotics and prescribing them inappropriately


About antibiotic awareness

Antibiotics are important medicines. They help fight infections that are caused by bacteria. Antibiotic resistance (when an antibiotic is no longer effective) is a major problem. It is one of the most significant threats to patients' safety in Europe. Antibiotic resistance is driven by overusing antibiotics and prescribing them inappropriately. It's important that we use antibiotics the right way, to slow down resistance and make sure these life-saving medicines remain effective for us and future generations.

Watch the “Take care, not antibiotics” videos on this page 

European Antibiotic Awareness Day (EAAD)

Every year, European Antibiotic Awareness Day is held on November 18. It's a Europe-wide public health initiative which encourages responsible use of antibiotics. The initiative is supported in England by the Department of Health and its Advisory Committee on Antimicrobial Resistance and Healthcare Associated Infections (ARHAI).

What is the problem?

Antibiotic resistance is an everyday problem in all hospitals across England and Europe. The spread of resistant bacteria in hospitals is a major issue for patients' safety.
  • Infections with antibiotic-resistant bacteria increase levels of disease and death, as well as the length of time people stay in hospitals.
  • Inappropriate use of antibiotics may increasingly cause patients to become colonised or infected with resistant bacteria.
  • Few new antibiotics are being developed. As resistance in bacteria grows, it will become more difficult to treat infection, and this affects patient care. 

What is causing this problem?

Inappropriate use and prescribing of antibiotics in hospitals is causing the development of resistance. 
Inappropriate use includes:
  • not completing a course of antibiotics as prescribed
  • skipping doses of antibiotics
  • not taking antibiotics at regular intervals
  • saving some for later
Inappropriate prescribing includes:
  • unnecessary prescription of antibiotics
  • unsuitable use of broad-spectrum antibiotics
  • wrong selection of antibiotics and inappropriate duration or dose of antibiotics

How can the problem be addressed?

Make antibiotic prescribing a strategic priority in hospitals by:
  • targeting antibiotic therapy
  • implementing structured antimicrobial stewardship plans
  • reviewing local surveillance and assessing microbiological data
Make antibiotic prescribing a priority in primary care by:
  • developing specific antibiotic prescribing guidelines for prescribers

Materials to support EAAD, November 18 2011 in England

To support EAAD and the promotion of sensible antibiotic use, the Department of Health (DH) and European Centre for Disease Prevention and Control (ECDC) have created information and educational materials for use in hospitals and primary care settings. You can download these and other materials from the DH website.

Thursday 5 February 2009

doctors arrogance

Gene fault 'ups antibiotic risk'



Antibiotics
Antibiotics are used to target serious infections
in 500 children is carrying a gene variation which means they are more likely to be damaged by a commonly used hospital antibiotic, a study suggests.

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